The difference between smoking, vaping, and using heated tobacco, according to a new scientific study Vaping versus smoking Don't Get Sucked In Toki Let's be real, what's the difference between vaping versus smoking cigarettes? We know that vaping contains no tobacco and far less chemicals than cigarettes but the keyword here is 'less'. Heated Tobacco Products, Cigarettes, and E Cigarettes: What's the Difference PMI Science Vaping vs. Smoking: Is One Really Safer Than the Other?